The tumor grows into the deep layers of the intestinal wall (IIA), penetrates through it, and spreads to the neighboring organs (IIB). There are no metastases to regional lymph nodes. Metastasis to a single organ (most often the liver or lungs) or to a group of distant lymph nodes (IVA), there are metastases to more than one organ or group of lymph nodes (IVB), or the cancer has spread to the peritoneal surface (IVC). At this stage, the size of the primary tumor and depth of invasion are irrelevant. Among the most severe symptoms are intestinal obstruction, retention of feces and gases, vomiting, and increased pain in the abdomen as well as in those organs affected by the secondary tumor. Often there is emaciation, there is disruption of the central nervous system. A diagnosis of colorectal cancer needs to be made early, as this will increase the chance of effective treatment. The risk of occurrence is higher in men, especially in the age group over 70-75 years old.